St Louis scientists cure diabetes in mice in just two weeks using converted human cells to produce insulin, giving hope to 400 million people
Researchers successfully converted enough human cells into the kind that produce the insulin hormone needed to combat diabetes
Mice with severe diabetes returned to normal blood sugar levels just two weeks after being infused with the converted cells
The mice were functionally cured for at least nine months and up to a year
The disease was previously been thought to be incurable
The treatment is far from being safe for humans yet as more tests are needed
Around 400 million people globally suffer from the disease
'These mice had very severe diabetes with blood sugar readings of more than 500 milligrams per deciliter of blood — levels that could be fatal for a person — and when we gave the mice the insulin-secreting cells, within two weeks their blood glucose levels had returned to normal and stayed that way for many months,' said principal investigator Dr Jeffrey R. Millman, an assistant professor of medicine and of biomedical engineering at Washington University.
The researchers initially discovered how to convert the cells several years ago but with certain flaws. After conversion, about a quarter of the cells were not insulin-producing but other kinds of beta cells such as liver cells.
The next step in the research will include testing the cells on larger animals and for longer periods of time.
#diabetes #type2diabetes #healthy #naturalremedies #diabetesmellitus,
#diabetesnaturaltreatment, #diabetescure
The process would also need to be automated if there was any hope of the treatment acting as an alternative to the insulin injections many diabetic patients currently rely on.
The research still remains encouraging as the first time a mouse, a mammal, has been functionally cured of the disease which has previously been thought to be incurable.
Researchers successfully converted enough human cells into the kind that produce the insulin hormone needed to combat diabetes
Mice with severe diabetes returned to normal blood sugar levels just two weeks after being infused with the converted cells
The mice were functionally cured for at least nine months and up to a year
The disease was previously been thought to be incurable
The treatment is far from being safe for humans yet as more tests are needed
Around 400 million people globally suffer from the disease
'These mice had very severe diabetes with blood sugar readings of more than 500 milligrams per deciliter of blood — levels that could be fatal for a person — and when we gave the mice the insulin-secreting cells, within two weeks their blood glucose levels had returned to normal and stayed that way for many months,' said principal investigator Dr Jeffrey R. Millman, an assistant professor of medicine and of biomedical engineering at Washington University.
The researchers initially discovered how to convert the cells several years ago but with certain flaws. After conversion, about a quarter of the cells were not insulin-producing but other kinds of beta cells such as liver cells.
The next step in the research will include testing the cells on larger animals and for longer periods of time.
#diabetes #type2diabetes #healthy #naturalremedies #diabetesmellitus,
#diabetesnaturaltreatment, #diabetescure
The process would also need to be automated if there was any hope of the treatment acting as an alternative to the insulin injections many diabetic patients currently rely on.
The research still remains encouraging as the first time a mouse, a mammal, has been functionally cured of the disease which has previously been thought to be incurable.
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